It was established, that clinical manifestation of acute dysentery caused by the polyagglutinable strain of Sonne shigellosis is characterized by acute onset of the disease, general toxic syndrome (high body temperature up mild pyrexia, chill, headache, low appetite) and in 6 - 24 hours followed by gastric indigestion resembling acute enterocolitis. In general, there have not been severe and lingering forms of the disease. Etiotropic and pathogenetic treatments are leading procedure in care of such patients.