Pathogenetic mechanisms of anemia development were studied in children with celiac disease to develop guiding rules for administration of complex therapy. It has been found out that celiac disease in children is accompanied by a high incidence of grave forms of anemia that adversely affect the course of the underlying condition. In anemic children with celiac disease, manifest pathophysiologic and pathobiochemical alterations in the hemoglobin and iron status are most common, with anemia of hyperregeneratory character being more prevalent. In children with celiac disease, the complex of therapy of anemia that do not respond to the instituted treatment options should be supplemented with protein preparations or activators of protein metabolism and with medicinal agents capable of correcting intestinal microflora.

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