The use of broncholytic medications in industrial workers with chronic obstructive lung diseases (COLD) caused by harmful working conditions is considered by the authors. Classification of COLD, detailed information about the use of long-term <$E beta sub 2>-agonists and cholinergic antagonists in treatment of patients with COLD are given in the article. Pathogenetic principles of action of medications used in treatment of patients with COLD are discussed in the article. Long-term cholinergic antagonist thiotropium bromidum is given much attention by the authors. The findings of the authors, concerning clinico-instrumental diagnostics of workers of underground mining, who had suffered from chronic obstructive lunge diseases are paid attention to. Early prescription of broncholytic medications to such patients is substantiated in the article.

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