Aiming to obtain the modificators of complex action, with co-inclusion of proteolytic enzymes and antimicrobial measures in a polymeric matrix, the possibility of formation of such structures, based on poly-N-vinyl caprolactam (PVC), is considered. As a result, we obtain the complex preparations of proteolytic enzymes and a preservative - 2-bromo-2-nitro-propane diol-1,3 (bronopol), containing the urea and possessing the prolonged action, being stable at acidic pH and storage. For the first time, the possibility of PVC stabilization by bronopol is shown. Basing on the IR- and NMR <$E nothing sup 13 roman C>-spectroscopy data, the possibility of obtaining the complexes of PVC with bronopol, containing 20 % of it, is confirmed.

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