30 children with the serious forms of infectious diseases were surveyed (purulent meningitis, acute meningococcemia, virus encephalitis, acute intestinal infection). In all groups of children, the contents of all fractions of fatty acids were changed. In a blood plasma of the patients of all groups, the contents of oleic and linoleic acids were authentically reduced, and the content of arachidonic acid in comparison with norm was increased. In the membranes of erythrocytes of all groups of patients, the content of polyunsaturated fatty acids was approximately triply increased, a significant rise of the level of linoleic and arachidonic acids was observed; linolenic acid absent in norm was found. The revealed changes in the spectrum of fatty acids of the patients with acute meningococcemia had significant differences in comparison with other groups, which can be used as an additional diagnostic criterion of this form of the disease.

• Виговська Оксана Валентинівна (медичні науки)

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